Drug Testing Locations in New Jersey

Accredited Drug Testing has 385 drug testing centers in 782 NJ cities.

Please select a city from the list below to find drug test centers in New Jersey.

Ensuring Safe Workplaces in New Jersey

Employers in New Jersey have a responsibility to maintain safe and productive work environments. Our extensive network of 386 test centers in 782 cities makes it easy for businesses to access our top-tier drug testing services and ensure compliance with state regulations.

Our drug testing services play a crucial role in reducing workplace accidents and improving overall productivity. By identifying potential substance abuse issues early, employers can take proactive steps to offer support and interventions that benefit both employees and the organization.

With our comprehensive testing solutions, New Jersey employers can gain peace of mind knowing they are protected against liability issues and can maintain insurance premiums. Our testing options include a range of substances, each administered by trained professionals in adherence to industry standards.

Moreover, our services enable companies to foster a culture of trust and safety. We offer flexible testing schedules and quick turnaround times, ensuring minimal disruption to daily operations while delivering precise and confidential results.

New Jersey Drug Free Workplace Programs

The state of New Jersey demonstrates a proactive stance in promoting drug-free environments within workplaces. Acknowledging the challenges posed by substance misuse, New Jersey encourages employers to implement comprehensive strategies aimed at maintaining safe and healthy work settings. Through various statewide initiatives, there is robust support for employers to adopt measures that prevent substance abuse and provide resources for intervention and treatment.

Emphasizing Education and Prevention, New Jersey places a significant focus on educating both employers and employees about the risks associated with substance misuse. Employers are encouraged to engage in training programs that help identify potential issues and offer guidance on crafting effective workplace policies. By fostering an atmosphere of awareness and support, New Jersey assists in creating an environment that encourages productivity and well-being for all.

How does the body eliminate Drugs

Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.

Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.

A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.

Issues of Concern

Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.

Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.

Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.

Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.

Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.

The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.

Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.

Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.

Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.

Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears

Mobile/On-Site Drug Testing

If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.

New Jersey Laws on Drugs

New Jersey's drug laws aim to promote safety and reduce substance abuse by implementing stringent penalties for the possession, distribution, or manufacturing of controlled substances. The state enforces severe consequences for narcotics offenses, including potential incarceration and substantial fines.

Drug trafficking convictions may result in harsher penalties, especially if these activities occur near schools. New Jersey law also mandates drug education and prevention programs, supporting rehabilitation over incarceration for first-time or non-violent offenders.

New Jersey Laws on Marijuana

As of recent changes in legislation, marijuana use and possession have been decriminalized and regulated for both medicinal and recreational purposes in New Jersey. Adults 21 and over can legally purchase and carry limited quantities of cannabis from licensed dispensaries.

Despite legalization, there are strict regulations on usage, similar to alcohol laws. It remains illegal to consume marijuana in public, and designated consumption areas are enforced to maintain public order. Driving under the influence of marijuana is strictly prohibited.

New Jersey Drug Resources

SAMHSA National Helpline
A confidential, free resource for drug abuse help.

NJ Addiction Services
State-run addiction services offering support.

NJ 211 Addiction Services
Resource for locating addiction help in NJ.

Community Substance Abuse Partnerships
Partnership services for substance abuse prevention.

Recovery Innovations
Provides comprehensive support and services.

Drug Policy Alliance
Fights for just and humane drug laws.

NJEA Health and Safety
Resources for workplace health and safety.

Business.NJ.gov
Guidance for NJ businesses on regulatory compliance.

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