Urine| Hair Follicle | Oral Fluid | Blood | ETG
Hair analysis has gained recognition as an effective means to uncover drug and alcohol consumption. The hair captures a timeline of alcohol and drug usage by embedding biomarkers within the hair strand's fibers. When taken near the scalp, hair tests can show a history of alcohol and drug use spanning up to roughly 90 days. The hair collection process is straightforward, it's relatively challenging to tamper with, and is convenient for transport.
A sample measuring 1.5 inches and holding around 200 hair strands (equivalent to the diameter of a #2 pencil) near the scalp is needed to achieve the 100mg of hair essential for both initial screening and subsequent confirmation. For EtG, add-ons, or tests exceeding 10 panels, it's advisable to use 150mg of the sample. It's best to measure the sample weight using a jeweler's scale. In the absence of scalp hair, a comparable quantity of body hair can be used. Our reference to head hair solely pertains to scalp hair, whereas body hair includes all other types (such as facial, axillary, etc.).
Process Overview
Key stages in processing a drug test in the lab include Accessioning, Screening, Extraction, and Confirmation.
Accessioning represents the sample's preliminary entry into the lab's system. This entails ensuring the sample's seal and shipment are intact, allocating it a unique LAN (Laboratory Accessioning Number), and filling in any missing data fields not covered by electronic custody records.
Screening offers an expedited evaluation for illicit drugs. Though effective in eliminating drug use suspicions in most samples, positive results from Screening must be verified to hold up in legal contexts. A presumptive positive from Screening requires further Confirmation.
Should Screening yield a presumptive positive result, additional hair is extracted from the original sample and readied for the Extraction step. In this phase, drugs are extracted from hair at a more diluted concentration compared to other methods (e.g., urine or saliva), which underscores the intricacy of hair drug analysis.
Confirmation of a positive Screening leads to testing via GC/MS, GC/MS/MS, or LC/MS/MS. Pre-confirmation steps include washing all presumptive positive samples as necessary. From Accessioning to Confirmation, the laboratory procedures are scrutinized in adherence to CAP (College of American Pathologists) Hair specifications and ISO / IEC 17025 standards.
Advantages of hair drug testing:
Limitations:
Note: The term "hair follicle tests" can be misleading, as the process analyzes the hair strand itself, not the follicle beneath the scalp.
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