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Accredited Drug Testing provides a diverse array of drug and alcohol testing services across our 36 locations in the Long Beach, California area. Offering both DOT and non-DOT urine tests, as well as breath alcohol, EtG, and hair follicle tests, we serve individuals, companies, and legal purposes. Results are delivered quickly, with SAMSA certified labs ensuring accuracy, and same-day appointments available. Most of our Long Beach locations are conveniently situated close to your home or workplace. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Contact us at (800) 221-4291 or easily register online. Select your preferred test and choose a location nearby to test for yourself, employees, or someone else. Our scheduling is fast and straightforward, with the option to call our department or book your test online any time. Our efficient, user-friendly process makes organizing drug tests near Long Beach completely hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Long Beach drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Long Beach, located in Los Angeles County, saw a 12% increase in opioid-related deaths in 2021.
In 2022, Long Beach Police Department reported over 300 drug-related arrests within the city limits.
Los Angeles County reported that Long Beach had 230 emergency room visits due to drug overdoses in 2021.
A 2022 survey revealed that 15% of high school students in Long Beach experimented with illicit drugs.
Long Beach's needle exchange program saw a 20% increase in participants from 2020 to 2022.
The Long Beach Health Department identified fentanyl as a major contributor to the spike in overdose deaths in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Long Beach, CA, are increasingly implementing stringent drug testing policies to ensure a safe and productive work environment. Many companies follow guidelines set by state and federal regulations like those by the California Department of Industrial Relations (https://www.dir.ca.gov/), ensuring compliance with workplace safety and health standards.
Some employers utilize pre-employment testing, random testing, and periodic testing, especially in industries where safety is a high priority, such as transportation or construction. These policies often align with the U.S. Department of Labor's guidelines (https://www.dol.gov/) to minimize drug-related workplace incidents effectively.
The city of Long Beach, CA, works in collaboration with Los Angeles County to combat drug abuse through various initiatives. The Long Beach Health Department (https://longbeach.gov/health/) has established programs focused on prevention, education, and harm reduction strategies targeting drug addiction and overdoses.
State-level efforts include support from the California Department of Health Care Services (https://www.dhcs.ca.gov/) which provides resources for treatment and recovery. Federal assistance is extended through grants and programs funded by the Substance Abuse and Mental Health Services Administration (https://www.samhsa.gov/), aiding local efforts in tackling the drug crisis.
In recent months, Long Beach, CA, has seen a surge in efforts targeting illegal drug activities. Local law enforcement, in collaboration with state agencies, conducted a series of operations aimed at dismantling drug networks. These operations have led to significant arrests and the seizure of substantial quantities of narcotics, including methamphetamine and fentanyl.
One notable incident involved the discovery of an underground drug lab set up in a residential neighborhood. The lab was sophisticated, equipped to produce large volumes of illegal substances. Following a tip-off, police raided the property, arresting several individuals involved in the manufacturing and distribution process. This bust highlights the ongoing challenges faced by law enforcement in combating domestic drug production.
Community groups in Long Beach have also stepped up, advocating for increased awareness and preventive measures against drug use. Recent workshops and seminars have been organized to educate the youth about the risks associated with drug abuse. These initiatives aim to reduce the demand for illicit drugs while supporting those affected by addiction.
Accredited Drug Testing offers fast, reliable employment screening services in Long Beach, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
Long Beach Health Department
LA o-drug Overdose Prevention Network
California Department of Health Care Services
Substance Abuse and Mental Health Services Administration
Narcotics Anonymous Southern California Region
Saving Ourselves Project
Al-Anon Family Groups
DBHIDS Provider Directory
California Alcohol and Drug Program Executives
California Healthline
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